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Autoimmune Disorders

How would you explain to a patient why autoantibodies, specifically TPO and thyroglobulin antibodies, are rising after 90 days of a full autoimmune Paleo diet with selenium and lifestyle changes, and now she’s worried about continuing with the intervention?

Dr. Amy Nett: This is a great question because we would love to see patients improving with only dietary and...

Are you seeing any correlation with particular microbes associated with MS? My patient has had EBV, has shown positive on 4+ on Citrobacter on the GI Effects panel we ran. Also discuss running Doctor’s Data to be current. Wanted your take on the viral microbial possible contribution.

Chris Kresser: Yeah, so in the literature, it’s well established that both viral infections and bacterial infections are contributors to...

Inflammation support, boswellia, curcumin, LDN, aromatic, medicine, colostrum, are extreme and immunoglobulin immunity.

Chris Kresser: I typically would use boswellia and curcumin and also LDN in this situation until they get their flare...

I know we’re not covering CIRS, chronic inflammatory response syndrome, in this course, but I’m hoping you can give a couple of pointers. I’m sensitive to mold, which triggers sinus issues and asthma. I live on a boat in the UK, which is probably the worse place on earth for me, but no other option in the short term. What would be your go-to supplements to reduce symptoms?

Chris Kresser: Yeah, CIRS is really complex, and it’s hard to give kind of basic recommendations. But if you are...

There’s a case study of a 31-year-old female who was diagnosed with ulcerative colitis in 2007. And the iron markers were presented and the iron markers basically showed low serum iron, low iron saturation, low TIBC, low UIBC, and high ferritin, ferritin being about 162. And in that, Chris, in that presentation Chris mentioned she has chronic disease. Before I read the conclusions about the case, I thought that she would have low iron and the high ferritin was just due to inflammation. This patient does not have low iron. I believe you, obviously, and I can see why I did all the other markers that are there, but how do we know for sure this woman doesn’t have low iron? What is there in the information you have supplied that shows that her iron is not low?

Dr. Amy Nett: This is a great question because you’re right, we don’t definitively know that she doesn’t have both...

Do you have any specific recommendation for pre-meningococcal vaccine detox and support for a teenager?

Chris Kresser: Tough question. So much there and I don’t want to go down the rabbit hole here, but I...

A patient is on AIP because of IBD and Hashimoto’s. Because of Lyme, she has taken several Beyond Balance supplements, and some of them contain seeds or seed oil. Should we try to find alternatives to those because of the seeds?

Dr. Amy Nett: I don’t know that the—so, I’m guessing you’re saying that you’re concerned about the omega-6 fatty acids?...

Have you seen changes on Cyrex Array 5 with the use of low-dose naltrexone?

Dr. Amy Nett: You know what? I don’t really use Cyrex Array 5 that often, so I haven’t tracked anyone...

I have a 52-year-old male with Graves’ disease who we are tracking with thyroid labs. His TSH is consistently 5 and occasional palpitations despite being on LDN, autoimmune Paleo diet, and various supplements over the past few years, including bugleweed, L-carnitine, meriva, etc. We ran the Cyrex Array 2, which was normal, and the Array 10. He’s completely gluten, dairy, and grain-free, so we didn’t do Arrays 3 or 4. Array 10 showed to be positive to egg whites, some nuts, most fruits and vegetables across the board, but negative to white rice and black beans. I spoke with Dr. Alexander at Cyrex about the discrepancy between Array 2 being negative and Array 10 being very positive, and he felt that the negative Array 2 definitely means the patient does not have leaky gut and that Array 10 was still positive due to immune system reaction to the food antigens in the system. Do you have any recommendations either for this patient and/or how to explain the test discrepancies?

Chris Kresser: Interesting question. Going back to the case, you mentioned he has Graves’ disease, but his TSH is 5,...

Would it add additional benefit to the Paleo template for autoimmune protocol for osteoarthritis?

Chris Kresser: It very well may. You know, some people, like I said, with any kind of inflammatory condition might...

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