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Cognitive Disorders

If someone is having an acute anxiety attack, how would you help them in the moment? That is to say, I understand a whole lot of testing and diet and lifestyle adjustments would be the key, but to support them during all that, is there a supplement you would suggest?

Dr. Amy Nett: I’m not entirely sure if you mean, like, how you would support someone actually during a panic...

If HVA is elevated, what are you thinking if other neurotransmitters are normal?

Dr. Amy Nett: For HVA, look at the HPA axis, what’s going on with stress levels. Metals is something else...

Can you explain a little bit more about the gut-brain barrier? I understand that cytokines from areas of inflammation in the body cross into the brain via the blood and can cause symptoms of depression, but I don’t really understand what that means. Do you think whenever you see depression there’s inflammation?

Chris Kresser:  Yeah, I think what you’re referring to, Justine, is the gut-brain axis and connection and then the inflammatory...

Have you ever used low-dose naltrexone for patients with a history of depression or low motivation in order to help with compliance for diet and lifestyle changes?

Dr. Amy Nett: I have not. I haven’t seen that as an indication for low-dose naltrexone. No. I’m just sort...

A 62-year-old female patient with delayed-onset psychosis. Low vitamin D level of 17 which is quite low. B12, folate, and hemoglobin levels are normal. Supplemented with 1,000 IU of vitamin D for three months and rechecked, and her levels are now 10 nanograms per milliliter. Any reason why it’s going lower with supplementation despite low dose and what to do next?

Chris Kresser:  One thing is, when you said B12, folate, and hemoglobin are normal, is that just serum B12, or...

Any suggestions, outside of rest, to deal with post-concussion syndrome?

Chris Kresser:  Well, post-concussion syndrome involves brain trauma, obviously, and whenever you’re talking about brain trauma, there’s microglial activation and...