Chris Kresser: Next question from Naveen, “What’s your take on polyreactivity and the idea that chronic inflammatory syndrome can create false-positive food reactivity?”
She is referring to the Cyrex array 3, 4 that she did, and 4 and 5 were positive for just about everything including markers for celiac. When she spoke to the Cyrex physician about the results, he suggested the idea of polyreactivity, which is just a concept when your immune system is hyperactivated [and] you’re going to be probably producing antibodies to a lot of different antigens in food. That doesn’t mean that the solution, in that case, is to remove all those foods from your diet, even in the short term, but certainly not in the long term, it would be to discover the source of that immune hypersensitivity, whether it’s an undiagnosed chronic infection or heavy metal toxicity or mold or other biotoxin exposure or something else, so that you can, as we’re often trying to do in Functional Medicine, address the root cause of the problem and reduce the immune hyperactivity, and then regain the oral tolerance to different foods.
So, in terms of Cyrex 12, that can be helpful. That’s where they test your antibodies to infectious antigens, [and] that doesn’t indicate, of course, whether you have a current infection; that’s a more challenging endeavor, and it’s not covered. We don’t cover that in this course, although a chronic infection module will, hopefully, be one of the first additional modules that we add to the practitioner program. It can be helpful in that regard, but you still will often have to do additional testing to see if the infection is current or just historical.