If someone has one functioning kidney, so a solitary kidney, no diabetes, and normal blood pressure, would you expect the EGFR to be a bit off? Would 78 be considered okay in this situation, or even with just one kidney, would you hope to have the results in the same range as if you had two kidneys?

Dr. Amy Nett:  So, I’m just going to say right now I’m actually not an expert in solitary kidney. I don’t know if there is a different range that would be considered acceptable. I can tell you, based on my training as a radiologist, I would most often look at EGFR normally in the setting to determine whether or not we could give contrast, so that is how I’m most familiar with EGFR. Of course, I look at it in labs pretty routinely for people who I assume have two kidneys. Most often people with a solitary kidney you might not even notice because they may have completely normal ranges, but with a solitary kidney, yes, you can have a slightly lower EGFR, and then you’re saying would 78 be considered okay in this situation? I think my question is what are you looking for? Because, to me, again, mostly from a radiology background, just functionally is the kidney okay? An EGFR of 60 or above would be okay, but an optimal range, yes, probably is going to be 90, but again what an optimal range for a solitary kidney is I don’t know. The question is how did this—kind of what is your concern, or what is the okay question? I would think like has it been trending, or is it stable? Because if the EGFR has been 78 throughout this person’s life, then that’s okay. So, let me read. The additional information that Justine gives, she says, “In this case, one is plump, and the other is shriveled,” so that’s often the case. This could have happened before birth or childhood, right? Yeah, it probably did happen either in utero or early childhood. I would agree. Then you mentioned the person struggles with energy, occasionally gets a kidney ache, but it is remedied very quickly by taking vitamin C. Okay.