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What do you think about using genomic reports to help determine the best macronutrient ratio for an individual such as the GXSlim report from Genetic Direction or Pathway Fit from Pathway Genomics?

Kelsey Marksteiner:  So I looked at those. I had never heard of them before. And they’re interesting. Personally at this point, I wouldn’t recommend that my clients go beyond what they’re getting in a 23andMe report to do those kind of reports. Because I kind of feel like you get the information in the 23andMe reports that they’re now allowed to give you. And so I just don’t think it’s worth the money necessarily. I went and looked at my own 23andMe report. Let me pull that up. Just a second. Kind of tell you guys what’s in it. And it looked like to me, Pathway Fit first of all was the only one I could find a sample report for. The other one was very vague. So I really did not get a good sense of what they included in there. So a little bit harder for me to tell, but they do pull from the 23andMe data so I can’t imagine it’s very different.

 

But they, in the Pathway Fit, when they talk about your caffeine tolerance, which 23andMe has, they tell you whether you’re going to do or they say that they’re going to tell you whether you do better on a low-carb or Mediterranean or low-fat kind of diet, which I’m not sure we can extrapolate at this point from the kind of data that you’re getting. I think they’re probably basing that on things like what the 23andMe report has, which for example they have a report unsaturated fat in a weight, which, like for me, the result it just says your weight is likely to be similar on diets high or low in saturated fat with the same number of total calories.

 

So you know that’s probably what they’re using to make a determination of whether someone should be on a low-carb, high-fat diet, or vice versa. I don’t know what information necessarily they would use to determine if you would do better on a Mediterranean diet. Maybe some of the heart disease risk factors, things like that. So I think you can probably guess these things with common sense to be honest and especially if you’re looking at someone’s 23andMe reports, I don’t think you’re going to get much more information than is already provided to you as a practitioner.

 

If someone’s really keen on doing it, I wouldn’t tell them absolutely not, it’s not going to give us anything. They can certainly try a lower-carb approach or a Mediterranean approach. Even maybe a lower-fat approach if they tend to do really, really great on carbs. There’s no reason not to experiment. So if they want to use that as a starting point and you educate them that this is only a starting point. We may need to experiment beyond this. This is not the end-all be-all results that is definitely going to work for you, then sure. But I certainly would not go out of my way to get this kind of report and I certainly wouldn’t recommend that my clients get a report like that.

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