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  4. This patient had elevated lysozyme at 651 and suppressed sIgA at 10.6. Does it mean he is not able to mount any immune response to the parasite or are the parasites are suppressing his immune response to survive? Or that they’re not pathogenic?

This patient had elevated lysozyme at 651 and suppressed sIgA at 10.6. Does it mean he is not able to mount any immune response to the parasite or are the parasites are suppressing his immune response to survive? Or that they’re not pathogenic?

Chris Kresser:  I don’t think we can say anything about what that means specifically. If you recall back to our gut unit and sIgA, all we know is that sIgA tends to be abnormal in situations like this. And we do know that it plays a very important role in maintaining a healthy gut immune environment. So when you see that it’s depressed, yes it could be either a result of the parasites, a cause of an environment that is then conducive to colonization by parasites and other organisms, or both. In most cases, it’s probably both. And as I said in the gut unit, that can often be the last thing that will improve in the treatment.

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